Thursday, 19 November 2020

Modern Diagnostic & Research Centre: Revealing the authenticity of COVID-19 tests

 Modern Diagnostic & Research Centre: Revealing the authenticity of COVID-19 tests

 


Coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus SARS-CoV-2. Most people who fall sick with COVID-19 disease experience mild to moderate symptoms and recover without special treatment. The virus that causes COVID-19 is mainly transmitted through droplets generated when an infected person coughs, sneezes, or exhales. 


There are two essential types of tests for COVID-19:


Comprehensively, two strategies of tests are available to identify SARS-CoV-2 that causes the Coronavirus disease 2019; First: Molecular assays that detect the presence of genetic material in the naso-pharyngeal cavity secretions and Second: Serological assays that detect the presence of antigen/antibodies in the appropriate samples.  


Molecular Diagnostics test: Molecular analysis depends on a standard molecular lab process of reverse-transcriptase Real-Time Polymerase Chain Reaction (RT-PCR), which replicates the infinitesimal small genetic material which is RNA in case of SARS-CoV-2, in the analyzed sample and categorizes the sample into positive/negative for the presence of virus. The procedure utilizes combination of primers/probes (short nucleic acid strands) specific to viral genetic material. A patient is advised this test dependent on the underlying indications. 

Antibody test: Antibody test can show whether the patient was recently or in past infected with COVID-19 virus and if the patient’s immune system has made antibodies trying to shield itself. It takes almost 12 days after the primary infection the immune system to produce enough antibodies to appear on an assay. 

More on COVID-19 tests: 

Viral Testing: 

Viral tests are prescribed to detect infection and is prescribed to both indicative as well as asymptomatic people. They are used to direct contact tracing, therapy choices, and isolations. Some of these tests are point-of-care tests, which means results might be accessible at the testing site in under 60 minutes.  

Antibody Testing: 

It is used to assess immune response to SARS-CoV-2 disease. MDRC doesn't suggest utilizing this testing as the sole strategy to conclude presence of infection. In specific circumstances, serologic examinations might be utilized to analyze people who present late or test individuals who are suspected to have any underlying condition brought about by SARS-CoV-2 infection (e.g., Multisystem Inflammatory Syndrome in Children; MIS-C). 

Serologic tests for SARS-CoV-2 contamination, are a significant instrument for epidemiologic investigations, for example, understanding the transmission dynamics of the infection in community. 

 

 How true are the lab tests used for COVID-19? 


Clinicians and patients require a test the accuracy of which they can trust. This has never been more evident than in the present scenario, given the consideration of COVID-19 testing and its function in assisting with ending the spread of COVID-19. This article clarifies what we know so far about both molecular as well as serological tests for the SARS-CoV-2 infection, and also understands that a lot of variables can influence an individual test outcome. 

 

Similarly, as with all lab tests, various variables decide the precision of a COVID-19 test outcome. These include not just the instrument and reagents used to process the test, but also include the sample collection techniques, the logistics as well as the physiological dynamics of the individual patient. 

 

Modern Diagnostic & Research Centre tests are described by their capability to differentiate a positive case (affected case) from a negative case (in which the presence of virus is undetected). 

 

Modern Diagnostic & Research Centre firmly believes in providing authentic test results. The four level “MDRC check” allows us keep a track and generate all results without any discrepancy. The whole Quality assurance system and the Internal Quality Control scheme allows us to deliver only the best results within the best possible turn-around-time.

 

 


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